Tuesday, May 25, 2010

Why don't we hear of "muscle cancer"? Why doesn't it appear?


Answer:
Cancers are much more common in cells of the body that multiply rapidly, like the skin and gut. There are tumors affecting more stable and even permanent cells like skeletal muscle and nerves, but the reason you don't hear about them is they are much less common.
It does occur, it's called sarcoma. And I have seen patients diagnosed with it in my days as a medical student.
There are only two kinds of tissues that are never invaded by cancer one is arteries and the other is cartilages. There are tumors of muscles but most are harmless and local.
There is a "muscle cancer" It is called rhabdomyosarcoma. Nasty cancer. They just found that it originates in mesothelial stem cells. Seems that all cancers come from stem cells, so if we start targeting these stem cells may get some cures.
Sarcoma is the type of cancer that affects the connective tissues of the body which includes
bone, fat, muscles, and blood vessels.Sarcoma is often a childhood cancer. It is aggressive and rare. Treatment options can be limited as it often does not receive research funding. Which may turn out to be ironic if the news received this week about Ewings Sarcoma and the potential to force the cancerous cell to return to its original status can be implemented in human beings.
http://www.news-medical.net/?id=25159...NCI: Soft Tissue Sarcoma
http://www.cancer.gov/cancertopics/types...NCI: Muscoskeletal Cancers
http://www.cancer.gov/cancertopics/cance...There are two branches of Sarcoma - the Soft Tissue sarcoma and the Bone Sarcoma.Bone Sarcoma includes Ewings Sarcoma, Osteosarcoma, and Chrondosarcoma.Soft Tissue Sarcoma includes:
Alveolar soft part sarcoma - cancer of blood vesselsAngiosarcoma - includes muscles of the heartDesmoplastic small round cell tumor - unknown origins, affects the soft tissues of abdominal cavityFibrosarcoma - fibrous connective tissue Hemangiosarcoma - blood vesselsLeiomyosarcoma - smooth and involuntary muscle cancerLiposarcoma - fat cells found deep within tissue (thigh)Neurofibrosarcoma - Peripheral nerves of the Central nervous systemRhabdomyosarcoma - affects the skeletal muscles and muscle tissueSynovial sarcoma - unknown origin

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