Sunday, October 25, 2009

Why do you have to wait 24 hours to give Neulasta after administration of chemotherapy?


Answer:
Neulasta is what is known as a granulocyte colony stimulating factor. It works by stimulating the bone marrow cells to divide more rapidly to increase the number of white blood cells which are introduced into the circulation.Chemotherapy works by disrupting mechanisms required for cells to divide. It is taken up by all the cells in the body which are actively dividing. Normally, cancer cells are more rapidly dividing that normal cells, and they take up more of the chemotherapy, but normal cells will also take it up giving some of the side effects. Your bone marrow cells are also affected by the chemotherapy and this is what causes the white blood cell count to go low in the first place. So, if you give Neulasta before the chemotherapy, you have just set up your bone marrow cells to be killed more by the chemotherapy as they are now more actively dividing. Hope this helps
I don't know.
I never asked questions, I just did it.

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